HCID 69288304, compound → HCID 21882747, compound

Participants

Reaction Steps

1.52 g of 2-amino-4-(2-p-tolyl-ethenyl)-3-nitropyridine (starting material N2) are dissolved in 30 ml of methanol and, after addition of 0.25 g of 10% strength palladium on carbon, are hydrogenated at 45° C. for 17 hours. The catalyst is filtered off, the filtrate is evaporated to dryness and the residue is chromatographed on a silica gel column (dichloromethane/methanol 25:1+1% triethylamine). Concentration of the pure fractions and drying in vacuo gives 0.80 g of the title compound as a brownish solid of m.p. 119–121° C. The mass spectrum shows the molecular peak MH+ at 228.2 Da.

Provenance & Evidence