化工社化工社 化学情報印刷レポート · 研究参考用
5-(3-Methoxy-4-nitrophenyl)-1,3,4-oxadiazol-2(3H)-one → 5-(4-Amino-3-methoxyphenyl)-1,3,4-oxadiazol-2(3H)-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-(3-Methoxy-4-nitrophenyl)-1,3,4-oxadiazol-2(3H)-one | HCID 21883906 | — |
| 反応物 | HCID 178418361 | HCID 178418361 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 5-(4-Amino-3-methoxyphenyl)-1,3,4-oxadiazol-2(3H)-one | HCID 21883858 | — |
反応手順
Hydrogen was introduced under atmospheric pressure into the mixture of 550 mg of 5-(3-methoxy-4-nitrophenyl)-3H-[1,3,4]oxadiazol-2-one, 100 mg of Pd/C and 50 ml of THF up to the theoretical uptake. Afterwards, the catalyst was filtered off with suction and the mixture was concentrated to dryness under reduced pressure.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07138414B2 |
| 出典データセット | uspto-grants-2006_11 |
| ORD ID | ord-d939b21e53a944c3aa5ddfdff4b7cc5a |
| 出典メモ | uspto-grants-2006_11 |