反应详情

温度

100 °C

The mixture of 500 mg of 3-methyl-4-nitrophenylhydrazine, 0.32 ml of methyl acetoacetate and 20 ml of toluene was heated to 100° C. for 8 hours. After cooling, the reaction mixture was concentrated under reduced pressure and the residue was stirred in t-butyl methyl ether. The solid was filtered off with suction and dried under reduced pressure.

1. temperatureAfter cooling
2. concentrationthe reaction mixture was concentrated under reduced pressure
3. filtrationThe solid was filtered off with suction
4. customdried under reduced pressure