Methyl 3-(2,2,2-trifluoroacetamido)thiophene-2-carboxylate → HCID 86628969, compound

HRID 72231Notes

Reaction equation

HRID 72231 reaction equation
[CH3:1][O:2][C:3]([C:5]1[S:6][CH:7]=[CH:8][C:9]=1[NH:10][C:11](=[O:16])[C:12]([F:15])([F:14])[F:13])=[O:4].CON(C)[C:20](=[O:24])[CH:21]([CH3:23])[CH3:22]>>[CH3:1][O:2][C:3]([C:5]1[S:6][C:7]([C:20](=[O:24])[CH:21]([CH3:23])[CH3:22])=[CH:8][C:9]=1[NH:10][C:11](=[O:16])[C:12]([F:13])([F:14])[F:15])=[O:4]

Participants

3

Reactant 2

HCID 2805185Methyl 3-(2,2,2-trifluoroacetamido)thiophene-2-carboxylateHCID 10866371N-Methoxy-N,2-dimethylpropanamide

Product 1

HCID 86628969HCID 86628969, compound

Procedure

3-(2,2,2-Trifluoroacetylamino)thiophene-2-carboxylic acid methyl ester and N-methoxy-N-methylisobutyramide were reacted by method M. The product with the molecular weight of 323.29 (C12H12F3NO4S) was obtained in this way; MS (ESI): 324 (M+H+).

Workup

  1. customThe product with the molecular weight of 323.29 (C12H12F3NO4S) was obtained in this way

Sources & evidence

ORD record
ord-6e19f31a2cab482880a04abcbc9022d4
Source dataset
uspto-grants-2014_09
Patent number
US08828991B2

Reaction notes

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