Sodium borohydride → HCID 24859708, compound

HRID 72232Notes

Reaction equation

HRID 72232 reaction equation
[C:1]([C:6]1[S:14][C:13]2[C:12](=[O:15])[N:11]([C:16]3[CH:21]=[CH:20][C:19]([N:22]4[CH2:28][CH2:27][CH2:26][N:25]([CH3:29])[CH2:24][CH2:23]4)=[CH:18][CH:17]=3)[CH:10]=[N:9][C:8]=2[CH:7]=1)(=[O:5])[CH:2]([CH3:4])[CH3:3].[BH4-].[Na+]>>[OH:5][CH:1]([C:6]1[S:14][C:13]2[C:12](=[O:15])[N:11]([C:16]3[CH:17]=[CH:18][C:19]([N:22]4[CH2:28][CH2:27][CH2:26][N:25]([CH3:29])[CH2:24][CH2:23]4)=[CH:20][CH:21]=3)[CH:10]=[N:9][C:8]=2[CH:7]=1)[CH:2]([CH3:3])[CH3:4]

Participants

3

Reactant 2

HCID 4311764Sodium borohydrideHCID 248597066-Isobutyryl-3-[4-(4-methyl[1,4]diazepan-1-yl)phenyl]-3H-thieno[3,2-d]pyrimidin-4-one

Product 1

HCID 24859708HCID 24859708, compound

Procedure

6-Isobutyryl-3-[4-(4-methyl[1,4]diazepan-1-yl)phenyl]-3H-thieno[3,2-d]pyrimidin-4-one and sodium borohydride were reacted by method Y. The product with the molecular weight of 412.56 (C22H28N4O2S) was obtained in this way; MS (ESI): 411 (M+H+).

Workup

  1. customThe product with the molecular weight of 412.56 (C22H28N4O2S) was obtained in this way

Sources & evidence

ORD record
ord-2b9121f71527485ca535fbaf7cbc43b9
Source dataset
uspto-grants-2014_09
Patent number
US08828991B2

Reaction notes

Loading…