Allyl bromide → HCID 68835490, compound

HRID 722422Notes

Reaction equation

HRID 722422 reaction equation
[CH3:1]OC1C=C2C(=CC=1)CC(=O)CC2.C(Br)C=C.[CH2:18]([C@:20]12[C:33]3[C:28](=[CH:29][C:30]([O:34][CH3:35])=[CH:31][CH:32]=3)[CH2:27][CH2:26][C:25]1=[CH:24][C:23](=[O:36])[CH2:22][CH2:21]2)[CH3:19]>>[CH2:18]([C@@:20]12[C:33]3[C:28](=[CH:29][C:30]([O:34][CH3:35])=[CH:31][CH:32]=3)[CH2:27][CH2:26][C:25]1=[CH:24][C:23](=[O:36])[CH2:22][CH2:21]2)[CH:19]=[CH2:1]

Participants

4

Reactant 3

HCID 7841Allyl bromideHCID 755826-Methoxy-1,2,3,4-tetrahydronaphthalen-2-oneHCID 25257703HCID 25257703, compound

Product 1

HCID 68835490HCID 68835490, compound

Procedure

(4aR)-4a-allyl-7-methoxy-4,4a,9,10-tetrahydro-3H-phenanthren-2-one was prepared in three steps from 6-methoxy-2-tetralone and allyl bromide in a manner analogous to that described for the synthesis of (4aR)-4a-ethyl-7-methoxy-4,4a,9,10-tetrahydro-3H-phenanthren-2-one in Preparations 1a to 1c.

Sources & evidence

ORD record
ord-da88a826bbec4ffcbcd48120b58badbf
Source dataset
uspto-grants-2006_11
Patent number
US07138406B2

Reaction notes

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