Trimellitic anhydride → HCID 21884358, compound

HRID 722483Notes

Reaction equation

[NH2:1][C:2]1[CH:3]=[C:4]([C:10]2[O:11][C:12]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:13]=3[N:14]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].[CH:20]1[C:25]([C:26]([OH:28])=[O:27])=[CH:24][C:23]2[C:29]([O:31][C:32](=O)[C:22]=2[CH:21]=1)=[O:30]>>[CH3:9][O:8][C:7]1[CH:6]=[CH:5][C:4]([C:10]2[O:11][C:12]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:13]=3[N:14]=2)=[CH:3][C:2]=1[N:1]1[C:29](=[O:30])[C:23]2[C:22](=[CH:21][CH:20]=[C:25]([C:26]([OH:28])=[O:27])[CH:24]=2)[C:32]1=[O:31]

Participants

Reactant 2

HCID 11089Trimellitic anhydride

HCID 10084758HCID 10084758, compound

Product 1

HCID 21884358HCID 21884358, compound

Procedure

Prepared by the method of Example 1b), from 2-(3-amino-4-methoxyphenyl)-5-chlorobenzoxazole (63 mg, 0.23 mmol) and 1,2,4-benzenetricarboxylic anhydride (50 mg, 0.26 mmol) the title compound was obtained, 62 mg (60%). 1H NMR (DMSO) δ 8.45(dd, 1H), 8.33(m, 3H), 8.12(d, 1H), 7.89(d, 1H), 7.80(d, 1H), 7.47(m, 2H), 3.89(s, 3H). MS 447 m/z (M−H)−.

Sources & evidence

ORD record: ord-7534367b72cc44d3871bd3cdde042603
Source dataset: uspto-grants-2006_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07138425B2

Reaction notes

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