HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21884400, compound → 2-(3-Amino-4-methoxyphenyl)-5-(benzofuran-2-yl)benzoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21884400 | HCID 21884400 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-(3-Amino-4-methoxyphenyl)-5-(benzofuran-2-yl)benzoxazole | HCID 21884591 | 86.3% |
Reaction Steps
A suspension of 2-(3-nitro-4-methoxyphenyl)-5-(benzofuran-2-yl)benzoxazole (50 mg, 0.13 mmol) in dioxane (10 ml) was placed under an atmosphere of argon. Palladium on carbon (10%) (10 mg) was added and the reaction purged with hydrogen and stirred at room temperature for 36 h. The reaction was filtered through a bed of celite and the filtrate concentrated to give the subtitle compound (40 mg, 86%). MS m/z 357.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07138425B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-58308e7288d84d54baaa8b63198f2575 |
| Source note | uspto-grants-2006_11 |