Trimellitic anhydride → 2-(5-(5-(Benzo[d][1,3]dioxol-5-yl)benzo[d]oxazol-2-yl)-2-methoxyphenyl)-1,3-dioxoisoindoline-5-carboxylic acid

Participants

Reaction Steps

Prepared by the method of Example 15f), from 2-(3-amino-4-methoxyphenyl-5-[3,4-(methylenedioxy)phenyl]benzoxazole (120 mg, 0.33 mmol) and 1,2,4-benzenetricarboxylic anhydride (70 mg, 0.36 mmol) the title compound was obtained (82 mg, 46%). 1H NMR (DMSO) δ 8.45(dd, 1H), 8.37–8.32(m, 3H), 8.12(d, 1H), 7.96(d, 1H), 7.79(d, 1H), 7.63(dd, 1H), 7.49(d, 1H), 7.33(d, 1H), 7.20(dd, 1H), 7.02(d, 1H), 6.06(2H, s), 3.88(s, 3H). MS m/z 535.0 (M+H)+.

Provenance & Evidence