(2,4-Dichlorophenyl)boronic acid → HCID 21884318, compound

HRID 722517Notes

Reaction equation

HRID 722517 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([C:12]2[O:13][C:14]3[CH:20]=[CH:19][C:18](Br)=[CH:17][C:15]=3[N:16]=2)[CH:7]=[CH:8][C:9]=1[O:10][CH3:11])([O-:3])=[O:2].[Cl:22][C:23]1[CH:28]=[C:27]([Cl:29])[CH:26]=[CH:25][C:24]=1B(O)O>>[N+:1]([C:4]1[CH:5]=[C:6]([C:12]2[O:13][C:14]3[CH:20]=[CH:19][C:18]([C:26]4[CH:25]=[CH:24][C:23]([Cl:22])=[CH:28][C:27]=4[Cl:29])=[CH:17][C:15]=3[N:16]=2)[CH:7]=[CH:8][C:9]=1[O:10][CH3:11])([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 2734659(2,4-Dichlorophenyl)boronic acidHCID 218843422-(3-Nitro-4-methoxyphenyl)-5-bromobenzoxazole

Product 1

HCID 21884318HCID 21884318, compound

Procedure

Prepared by the method of Example 15d), from 2-(3-nitro-4-methoxyphenyl)-5-bromobenzoxazole (200 mg, 0.57 mmol) and 2,4-dichlorophenylboronic acid (164 mg, 0.86 mmol) the subtitle compound was obtained, (148 mg, 62%). 1H NMR (DMSO) δ 8.69(s, 1H), 8.51(d, 1H), 7.93(d, 1H), 7.84(s, 1H), 7.60(m, 3H), 4.12(s, 3H). MS 415 m/z (M+H)+.

Sources & evidence

ORD record
ord-df9013eb06e94beca7ae28f3e9fdf38c
Source dataset
uspto-grants-2006_11
Patent number
US07138425B2

Reaction notes

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