Trimellitic anhydride → HCID 135839382, compound

HRID 722536Notes

Reaction equation

[NH2:1][C:2]1[CH:3]=[CH:4][C:5]([O:23]CC2C=COC=2)=[C:6]([C:8]2[O:9][C:10]3[CH:16]=[CH:15][C:14]([C:17]4[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=4)=[CH:13][C:11]=3[N:12]=2)[CH:7]=1.[CH:30]1[C:35]([C:36]([OH:38])=[O:37])=[CH:34][C:33]2[C:39]([O:41][C:42](=O)[C:32]=2[CH:31]=1)=[O:40]>>[OH:23][C:5]1[CH:4]=[CH:3][C:2]([N:1]2[C:39](=[O:40])[C:33]3[C:32](=[CH:31][CH:30]=[C:35]([C:36]([OH:38])=[O:37])[CH:34]=3)[C:42]2=[O:41])=[CH:7][C:6]=1[C:8]1[O:9][C:10]2[CH:16]=[CH:15][C:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[CH:13][C:11]=2[N:12]=1

Participants

Reactant 2

HCID 11089Trimellitic anhydride

HCID 21884491HCID 21884491, compound

Product 1

HCID 135839382HCID 135839382, compound

Procedure

Prepared by the method of Example 1b), from 2-(5-amino-2-(3-furanylmethoxy)phenyl)-5-phenylbenzoxazole (144 mg, 0.28 mmol) and 1,2,4-benzenetricarboxylic anhydride (73 mg, 0.38 mmol) the title compound was obtained (100 mg, 55%). 1H NMR (DMSO) δ 8.48(dd, 1H), 8.39(s, 1H), 8.25(d, 1H), 8.21(d, 1H), 8.17(d, 1H), 8.00(d, 1H), 7.82(m, 3H), 7.70(dd, 1H), 7.57(t, 2H), 7.46(t, 1H), 7.38(d, 1H). MS 477 m/z (M+H)+.

Sources & evidence

ORD record: ord-8deefa4d53b54712bf2fd49fc7d1e160
Source dataset: uspto-grants-2006_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07138425B2

Reaction notes

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