2-Amino-5-methylphenol → HCID 21884435, compound

HRID 722562Notes

Reaction equation

HRID 722562 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[CH:4][C:3]=1[OH:9].[F:10][C:11]1[CH:19]=[CH:18][C:17]([N+:20]([O-:22])=[O:21])=[CH:16][C:12]=1[C:13](Cl)=[O:14]>>[OH:9][C:3]1[CH:4]=[C:5]([CH3:8])[CH:6]=[CH:7][C:2]=1[NH:1][C:13](=[O:14])[C:12]1[CH:16]=[C:17]([N+:20]([O-:22])=[O:21])[CH:18]=[CH:19][C:11]=1[F:10]

Participants

3

Reactant 2

HCID 760822-Amino-5-methylphenolHCID 109765702-Fluoro-5-nitrobenzoyl chloride

Product 1

HCID 21884435HCID 21884435, compound

Procedure

Prepared by the method of Example 15a), from 2-amino-5-methylphenol (605 mg, 4.9 mmol) and 2-fluoro-5-nitrobenzoyl chloride (1.00 g, 5.0 mmol) the subtitle compound was obtained. The product was used directly in the next step without purification.

Sources & evidence

ORD record
ord-2311fb4af2314a7385f6dbc57317c7c6
Source dataset
uspto-grants-2006_11
Patent number
US07138425B2

Reaction notes

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