2-Amino-4,6-dichlorophenol → N-(2-Hydroxy-3,5-dichlorophenyl)-2-fluoro-5-nitrobenzamide

HRID 722577노트

반응식

HRID 722577 반응식
[NH2:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4]([Cl:9])[C:3]=1[OH:10].[F:11][C:12]1[CH:20]=[CH:19][C:18]([N+:21]([O-:23])=[O:22])=[CH:17][C:13]=1[C:14](Cl)=[O:15]>>[OH:10][C:3]1[C:4]([Cl:9])=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=1[NH:1][C:14](=[O:15])[C:13]1[CH:17]=[C:18]([N+:21]([O-:23])=[O:22])[CH:19]=[CH:20][C:12]=1[F:11]

참가 물질

3

반응물 2

HCID 106992-Amino-4,6-dichlorophenolHCID 109765702-Fluoro-5-nitrobenzoyl chloride

생성물 1

HCID 21884581N-(2-Hydroxy-3,5-dichlorophenyl)-2-fluoro-5-nitrobenzamide

실험 절차

Prepared by the method of Example 15a), from 2-amino-4,6-dichlorophenol (409 mg, 2.3 mmol) and 2-fluoro-5-nitrobenzoyl chloride (468 mg, 2.3 mmol) the subtitle compound was obtained. The product was used directly in the next step without purification.

출처 및 근거

ORD 기록
ord-b90a80d7e4e44190ac25b1e57e8dd713
출처 데이터셋
uspto-grants-2006_11
특허 번호
US07138425B2

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