HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-4-(trifluoromethyl)phenol → N-(2-Hydroxy-5-trifluoromethylphenyl)-2-fluoro-5-nitrobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-4-(trifluoromethyl)phenol | HCID 120246 | — |
| Reactant | 2-Fluoro-5-nitrobenzoyl chloride | HCID 10976570 | — |
| Product | N-(2-Hydroxy-5-trifluoromethylphenyl)-2-fluoro-5-nitrobenzamide | HCID 21884558 | — |
Reaction Steps
Prepared by the method of Example 15a), from 2-amino-4-trifluoromethylphenol (407 mg, 2.3 mmol) and 2-fluoro-5-nitrobenzoyl chloride (468 mg, 2.3 mmol) the subtitle compound was obtained. The product was used directly in the next step without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07138425B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-d529938645dc4604aa966d30da2ea4c8 |
| Source note | uspto-grants-2006_11 |