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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 722599Generated: October 25, 2026

2-Amino-m-cresol → N-(2-Hydroxy-6-methylphenyl)-2-fluoro-5-nitrobenzamide

https://huagongshe.com/reaction/722599

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-m-cresolHCID 3014138—
Reactant2-Fluoro-5-nitrobenzoyl chlorideHCID 10976570—
ProductN-(2-Hydroxy-6-methylphenyl)-2-fluoro-5-nitrobenzamideHCID 21884425—

Reaction Steps

Prepared by the method of Example 15a), from 2-amino-3-methylphenol (283 mg, 2.3 mmol) and 2-fluoro-5-nitrobenzoyl chloride (468 mg, 2.3 mmol) the subtitle compound was obtained. The product was used directly in the next step without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07138425B2
Source datasetuspto-grants-2006_11
ORD IDord-520a89de03274d28b2c604644b7e0dfd
Source noteuspto-grants-2006_11