Benzoyl chloride, 3-nitro- → HCID 69585022, compound

HRID 722603Notes

Reaction equation

HRID 722603 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][C:11]=1[NH2:12])[C:5]([O:7][CH3:8])=[O:6].[N+:13]([C:16]1[CH:17]=[C:18]([CH:22]=[CH:23][CH:24]=1)[C:19](Cl)=[O:20])([O-:15])=[O:14]>>[CH3:8][O:7][C:5](=[O:6])[C:4]1[CH:9]=[CH:10][C:11]([NH:12][C:19](=[O:20])[C:18]2[CH:22]=[CH:23][CH:24]=[C:16]([N+:13]([O-:15])=[O:14])[CH:17]=2)=[C:2]([OH:1])[CH:3]=1

Participants

3

Reactant 2

HCID 8495Benzoyl chloride, 3-nitro-HCID 7020619Benzoic acid, 4-amino-3-hydroxy-, methyl ester

Product 1

HCID 69585022HCID 69585022, compound

Procedure

Prepared by the method of Example 15b), from methyl 3-hydroxy-4-aminobenzoate (12.94 g, 77.0 mmol) and 3-nitrobenzoyl chloride (14.29 g, 77.0 mmol) the subtitle compound was obtained (22.45 g, 92%). The product was used directly in the next step without purification.

Sources & evidence

ORD record
ord-069fb39366f14576a496ae5eeefb5b0f
Source dataset
uspto-grants-2006_11
Patent number
US07138425B2

Reaction notes

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