HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid monohydrate → 2-(3-Nitro-4-chlorophenyl)-5-phenylbenzoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| Reactant | N-(5-Phenyl-2-hydroxyphenyl)-3-nitro-4-chlorobenzamide | HCID 21884357 | — |
| Product | 2-(3-Nitro-4-chlorophenyl)-5-phenylbenzoxazole | HCID 21884327 | — |
Reaction Steps
Prepared by the method of Example 15c), from N-(5-phenyl-2-hydroxyphenyl)-3-nitro-4-chlorobenzamide (3.76 g, 10 mmol) and p-toluenesulfonic acid monohydrate (3.80 g, 20 mmol) the subtitle compound was obtained (1.28 g, 40%). MS 351.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07138425B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-da246c55d9c044708b7ef0bc9b6bc781 |
| Source note | uspto-grants-2006_11 |