(4-Fluoro-3-formylphenyl)boronic acid → HCID 21884419, compound

HRID 722629Notes

Reaction equation

HRID 722629 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([C:12]2[O:13][C:14]3[CH:20]=[CH:19][C:18](Br)=[CH:17][C:15]=3[N:16]=2)[CH:7]=[CH:8][C:9]=1[O:10][CH3:11])([O-:3])=[O:2].[F:22][C:23]1[CH:28]=[CH:27][C:26](B(O)O)=[CH:25][C:24]=1[CH:32]=[O:33]>>[N+:1]([C:4]1[CH:5]=[C:6]([C:12]2[O:13][C:14]3[CH:20]=[CH:19][C:18]([C:26]4[CH:27]=[CH:28][C:23]([F:22])=[C:24]([CH:32]=[O:33])[CH:25]=4)=[CH:17][C:15]=3[N:16]=2)[CH:7]=[CH:8][C:9]=1[O:10][CH3:11])([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 2778651(4-Fluoro-3-formylphenyl)boronic acidHCID 218843422-(3-Nitro-4-methoxyphenyl)-5-bromobenzoxazole

Product 1

HCID 21884419HCID 21884419, compound

Procedure

Prepared by the method of Example 15d), from 2-(3-nitro-4-methoxyphenyl)-5-bromobenzoxazole (200 mg, 0.57 mmol) and 4-fluoro-3-formylphenylboronic acid (143 mg, 0.85 mmol) the subtitle compound was obtained (146 mg, 44%). MS 393 m/z (M+H)+.

Sources & evidence

ORD record
ord-531aa495cf9e41d98cd1158b6fa68fb7
Source dataset
uspto-grants-2006_11
Patent number
US07138425B2

Reaction notes

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