Trimellitic anhydride → HCID 21884645, compound

Participants

Reaction Steps

Prepared by the method of Example 15f), from 2-(3-amino-6-methoxyphenyl)-5-(3-chloro-4-fluorophenyl)benzoxazole (60 mg, 0.16 mmol) and 1,2,4-benzenetricarboxylic anhydride (31 mg, 0.16 mmol) the title compound was obtained (75 mg, 86%). 1H NMR (DMSO) δ 13.80(s, 1H), 8.43(d, 1H), 8.32(s, 1H), 8.21(d, 1H), 8.15(s, 1H), 8.10(d, 1H), 7.99(dd, 1H), 7.88(d, 1H), 7.75(m, 3H), 7.53(t, 1H), 7.47(d, 1H), 4.03(s, 3H). MS 542.6 m/z (M+H)+.

Provenance & Evidence