Trimellitic anhydride → HCID 21884374, compound

HRID 722644Notes

Reaction equation

[NH2:1][C:2]1[CH:3]=[C:4]([C:10]2[O:11][C:12]3[CH:18]=[CH:17][C:16]([C:19]4[O:20][C:21]5[CH:27]=[CH:26][CH:25]=[CH:24][C:22]=5[CH:23]=4)=[CH:15][C:13]=3[N:14]=2)[C:5]([O:8][CH3:9])=[CH:6][CH:7]=1.[CH:28]1[C:33]([C:34]([OH:36])=[O:35])=[CH:32][C:31]2[C:37]([O:39][C:40](=O)[C:30]=2[CH:29]=1)=[O:38]>>[CH3:9][O:8][C:5]1[C:4]([C:10]2[O:11][C:12]3[CH:18]=[CH:17][C:16]([C:19]4[O:20][C:21]5[CH:27]=[CH:26][CH:25]=[CH:24][C:22]=5[CH:23]=4)=[CH:15][C:13]=3[N:14]=2)=[CH:3][C:2]([N:1]2[C:37](=[O:38])[C:31]3[C:30](=[CH:29][CH:28]=[C:33]([C:34]([OH:36])=[O:35])[CH:32]=3)[C:40]2=[O:39])=[CH:7][CH:6]=1

Participants

Reactant 2

HCID 11089Trimellitic anhydride

HCID 21884303HCID 21884303, compound

Product 1

HCID 21884374HCID 21884374, compound

Procedure

Prepared by the method of Example 15f), from 2-(3-amino-6-methoxyphenyl)-5-(2-benzofuranyl)benzoxazole (105 mg, 0.29 mmol) and 1,2,4-benzenetricarboxylic anhydride (57 mg, 0.29 mmol) the title compound was obtained (98 mg, 63%). 1H NMR (DMSO) δ 13.74(s, 1H), 8.43(dd, 1H), 8.32(d, 2H), 8.21(d, 1H), 8.10(d, 1H), 8.02(dd, 1H), 7.92(d, 1H), 7.72(dd, 1H), 7.67(t, 2H), 7.54(s, 1H), 7.47(d, 1H), 7.31(m, 2H), 4.03(s, 3H). MS 531.2 m/z (M+H)+.

Sources & evidence

ORD record: ord-af256f8d3a46493094e43dc93e7d066c
Source dataset: uspto-grants-2006_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07138425B2

Reaction notes

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