(2H-1,3-benzodioxol-5-yl)boronic acid → HCID 69585120, compound

HRID 722646Notes

Reaction equation

HRID 722646 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([C:12]2[O:13][C:14]3[CH:20]=[CH:19][C:18](Br)=[CH:17][C:15]=3[N:16]=2)[C:7]([O:10][CH3:11])=[CH:8][CH:9]=1)([O-:3])=[O:2].[CH2:22]1[O:30][C:29]2[CH:28]=[CH:27][C:26](B(O)O)=[CH:25][C:24]=2[O:23]1>>[N+:1]([C:4]1[CH:5]=[C:6]([C:12]2[O:13][C:14]3[CH:20]=[CH:19][C:18]([C:27]4[CH:26]=[CH:25][C:24]5[O:23][CH2:22][O:30][C:29]=5[CH:28]=4)=[CH:17][C:15]=3[N:16]=2)[C:7]([O:10][CH3:11])=[CH:8][CH:9]=1)([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 2734371(2H-1,3-benzodioxol-5-yl)boronic acidHCID 21884587HCID 21884587, compound

Product 1

HCID 69585120HCID 69585120, compound

Procedure

Prepared by the method of Example 15d), from 2-(3-nitro-6-methoxyphenyl)-5-bromobenzoxazole (400 mg, 1.14 mmol) and 3,4-methylenedioxyphenylboronic acid (285 mg, 1.71 mmol) the subtitle compound was obtained (270 mg, 48%). The product was used directly in the next step without purification.

Sources & evidence

ORD record
ord-312e562e05e14a9093948404c6f1c68f
Source dataset
uspto-grants-2006_11
Patent number
US07138425B2

Reaction notes

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