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(2H-1,3-benzodioxol-5-yl)boronic acid → 2-(3-Nitro-6-propylaminophenyl)-5-(3,4-methylenedioxyphenyl)benzoxazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (2H-1,3-benzodioxol-5-yl)boronic acid | HCID 2734371 | — |
| 反応物 | 2-(5-bromo-1,3-benzoxazol-2-yl)-4-nitro-N-propylaniline | HCID 5303802 | — |
| 生成物 | 2-(3-Nitro-6-propylaminophenyl)-5-(3,4-methylenedioxyphenyl)benzoxazole | HCID 69585107 | — |
反応手順
Prepared by the method of Example 15d), from 2-(3-nitro-6-propylaminophenyl)-5-bromobenzoxazole (400 mg, 1.59 mmol) and 3,4-methylenedioxyphenylboronic acid (264 mg, 1.59 mmol) the subtitle compound was obtained (337 mg, 51%). The product was used directly in the next step without purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07138425B2 |
| 出典データセット | uspto-grants-2006_11 |
| ORD ID | ord-6b49128cb8404e61a4086c99d8bb3add |
| 出典メモ | uspto-grants-2006_11 |