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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 722659Generated: October 27, 2026

2-(3-Nitro-6-propylaminophenyl)-5-(2-benzothiophenyl)benzoxazole → 2-(3-Amino-6-propylaminophenyl)-5-(2-benzothiophenyl)benzoxazole

https://huagongshe.com/reaction/722659

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Nitro-6-propylaminophenyl)-5-(2-benzothiophenyl)benzoxazoleHCID 21884309—
CatalystZincHCID 23994—
Product2-(3-Amino-6-propylaminophenyl)-5-(2-benzothiophenyl)benzoxazoleHCID 21884299—

Reaction Steps

Prepared by the method of Example 47b), from 2-(3-nitro-6-propylaminophenyl)-5-(2-benzothiophenyl)benzoxazole (386 mg, 0.90 mmol) and zinc (589 mg, 9.0 mmol) the subtitle compound was obtained (154 mg, 100%). MS 400.3 m/z (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07138425B2
Source datasetuspto-grants-2006_11
ORD IDord-f821177b2f034240977629a06b7c402a
Source noteuspto-grants-2006_11