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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 722664Generated: October 27, 2026

2-(3-Nitro-6-propylaminophenyl)-5-(4-chlorophenyl)benzoxazole → 2-(3-Amino-6-propylaminophenyl)-5-(4-chlorophenyl)benzoxazole

https://huagongshe.com/reaction/722664

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Nitro-6-propylaminophenyl)-5-(4-chlorophenyl)benzoxazoleHCID 21884340—
CatalystZincHCID 23994—
Product2-(3-Amino-6-propylaminophenyl)-5-(4-chlorophenyl)benzoxazoleHCID 21884441—

Reaction Steps

Prepared by the method of Example 47b), from 2-(3-nitro-6-propylaminophenyl)-5-(4-chlorophenyl)benzoxazole (284 mg, 0.70 mmol) and zinc (455 mg, 7.0 mmol) the subtitle compound was obtained (264 mg, 99%). The product was used directly in the next step without purification

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07138425B2
Source datasetuspto-grants-2006_11
ORD IDord-c5342dff12274d64a220f4e8956683c3
Source noteuspto-grants-2006_11