HCID 58743377, compound → HCID 58743394, compound

Participants

Reaction Steps

To a solution of azide 95 (25 mg, 0.06 mmol) in MeOH (1.5 mL) at room temperature, Pd—C (10% wt, 16 mg, 0.015 mmol) was added. The mixture was purged with a stream of dry Ar, and then H2. The reaction was stirred overnight under a H2 atmosphere (1 atm). The catalyst was filtered off through a 0.45 μm teflon filter in polypropylene housing, washing the filter with MeOH (15 mL) and the solvent was evaporated in vacuo to obtain amine 96 as a white solid (22 mg, 94% yield).

Provenance & Evidence