HCID 54031872, compound → HCID 54031873, compound

HRID 722884Notes

Reaction equation

HRID 722884 reaction equation
[C:1]([O:5][C:6](=[O:20])[CH2:7][C@H:8]([CH2:12][C@H:13]([CH3:19])[CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[C:9]([OH:11])=[O:10])([CH3:4])([CH3:3])[CH3:2].C(OC(=O)C[C@@H](C(N1[C@H](C)[C@H](C2C=CC=CC=2)OC1=O)=O)C[C@@H](C)CCCCC)(C)(C)C>>[C:1]([O:5][C:6](=[O:20])[CH2:7][C@H:8]([CH2:12][C@@H:13]([CH3:19])[CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[C:9]([OH:11])=[O:10])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 54031872HCID 54031872, compoundHCID 57316752HCID 57316752, compound

Product 1

HCID 54031873HCID 54031873, compound

Procedure

A procedure similar to that used for compound 157 was used except that ester 165 (8.42 g, 18.89 mmol) was used as a reactant to give 166 as an oil (5.81 g). The material was used directly in the next step. MS (APCI) m/z 285 (M−1, 100%).

Sources & evidence

ORD record
ord-91cb3f5c46e74d34bd5022b3bef39589
Source dataset
uspto-grants-2006_11
Patent number
US07138542B2

Reaction notes

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