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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 722934Generated: October 25, 2026

5-Chlorovaleryl chloride → 5-Chloro-1-(2,2-dimethyl-3,4-dihydro-2H-chromen-6-yl)-1-pentanone

https://huagongshe.com/reaction/722934

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chlorovaleryl chlorideHCID 74089—
Reactant2,2-DimethylchromanHCID 136936—
Product5-Chloro-1-(2,2-dimethyl-3,4-dihydro-2H-chromen-6-yl)-1-pentanoneHCID 21887307—

Reaction Steps

Using 2,2-dimethylchroman (19.7 g) and 5-chlorovaleryl chloride (20.7 g) according to the same method as that of Reference Example 1, the title compound was obtained as colorless crystals (22.0 g) having a melting point of 50 to 51° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07138533B2
Source datasetuspto-grants-2006_11
ORD IDord-f0bc7c19ca004556b8b322dc57b2b846
Source noteuspto-grants-2006_11