反应详情

Using 8-(5-{[2-(2-chlorophenyl)ethyl]amino}pentanoyl)-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one hydrochloride (205 mg, 0.5 mmol) obtained in Example 39 and citric acid (96 mg, 0.5 mmol) according to the same method as that of Example 360, the title compound was obtained as colorless crystals (278 mg) having a melting point of 100 to 102° C. (dec). elementary analysis as C24H27ClN2O2.C6H8O7 calculation value: C, 59.75; H, 5.85; N, 4.65. experimental value: C, 59.34; H, 6.21; N, 4.39.