反应详情

The e.e. of N-benzyloxycarbonyl-3-hydroxypyrrolidine was measured by analytical HPLC with a chiral column [Chiralpak AS (Daicel), 250 mm×4.6 mm; eluent: hexane/isopropanol (100:4); flow rate: 1 ml/min; detection wavelength: 210 nm; retention times: 32.9 min for the (S)-form and 36.7 min for the (R)-form]. (R)-N-benzyloxycarbonyl-3-hydroxypyrrolidine was obtained in as 85% e.e.

1. custom32.9 min