Dimethylformamide → N,N,N'-trimethyl-N'-(4-nitrophenyl)-1,2-ethanediamine

Participants

Role	Name	HCID	Charge
Reactant	Dimethylformamide	HCID 6228	—
Reactant	p-Fluoronitrobenzene	HCID 9590	—
Reactant	Potassium Carbonate	HCID 11430	—
Reactant	1,2-Ethanediamine, N1,N1,N2-trimethyl-	HCID 67338	—
Solvent	Water	HCID 962	—
Product	N,N,N'-trimethyl-N'-(4-nitrophenyl)-1,2-ethanediamine	HCID 21873305	—

Reaction Steps

A mixture of N,N,N′-trimethylethane-1,2-diamine (2.17 g), potassium carbonate (3.0 g), 4-nitrofluorobenzene and dimethylformamide (30 ml) was stirred for 72 hours. The reaction mixture was diluted with water and extracted with ethyl acetate. The organic phase was washed with water and saturated brine, dried and concentrated. The product with the molecular weight of 223.28 (C11H17N3O2); MS (ESI): 224 ([M+H]+), was obtained in this way.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07141561B2
Source dataset	uspto-grants-2006_11
ORD ID	ord-d79caca2d30e429c984791767474afae
Source note	uspto-grants-2006_11