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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 72335Generated: October 26, 2026

2-(Bromomethyl)pyridine → Carbamic acid 1-{3-[4-(pyridin-2-ylmethoxy)-phenyl]-isoxazol-5-yl}-ethyl ester

https://huagongshe.com/reaction/72335

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Bromomethyl)pyridineHCID 564209—
ReactantCarbamic acid 1-[3-(4-benzyloxy-phenyl)-isoxazol-5-yl]-ethyl esterHCID 46893245—
ProductCarbamic acid 1-{3-[4-(pyridin-2-ylmethoxy)-phenyl]-isoxazol-5-yl}-ethyl esterHCID 66617541—

Reaction Steps

The compound was synthesized using carbamic acid 1-[3-(4-benzyloxy-phenyl)-isoxazol-5-yl]-ethyl ester of example 117 in the same manner as in Example 10 by debenzylation following reaction with 2-bromomethylpyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08828992B2
Source datasetuspto-grants-2014_09
ORD IDord-3cae1a8ecd6e471b98a7d5133f42f89e
Source noteuspto-grants-2014_09