Allyl bromide → HCID 21873363, compound

Participants

Reaction Steps

Potassium hydride (30% in oil, 40 mg) was added to a solution of 1-allyl-1-(4-benzyloxyphenyl)-3-(4-phenoxyphenyl)urea (133 mg) in THF (3 mL) at −78° C. After 30 minutes, allyl bromide (30 μL) was added. After 14 hours at room temperature, the solution was diluted with dichloromethane and washed with saturated sodium bicarbonate solution. The organic phase was dried and concentrated. The product with the molecular weight of 490.61 (C32H30N2O3); MS (ESI): 491 ([M+H]+), was obtained in this way.

Provenance & Evidence