1,2-Dibromoethane → 1-[4-(2-Bromoethoxy)phenyl]-3-(4-cyclopentyloxyphenyl)-1,3-dihydroimidazol-2-one

HRID 723369Notes

Reaction equation

HRID 723369 reaction equation
[CH:1]1([O:6][C:7]2[CH:12]=[CH:11][C:10]([N:13]3[CH:17]=[CH:16][N:15]([C:18]4[CH:23]=[CH:22][C:21]([OH:24])=[CH:20][CH:19]=4)[C:14]3=[O:25])=[CH:9][CH:8]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[Br:26][CH2:27][CH2:28]Br>>[Br:26][CH2:27][CH2:28][O:24][C:21]1[CH:20]=[CH:19][C:18]([N:15]2[CH:16]=[CH:17][N:13]([C:10]3[CH:9]=[CH:8][C:7]([O:6][CH:1]4[CH2:2][CH2:3][CH2:4][CH2:5]4)=[CH:12][CH:11]=3)[C:14]2=[O:25])=[CH:23][CH:22]=1

Participants

3

Reactant 2

HCID 78391,2-DibromoethaneHCID 218733401-(4-Cyclopentyloxyphenyl)-3-(4-hydroxyphenyl)-1,3-dihydroimidazol-2-one

Product 1

HCID 218733301-[4-(2-Bromoethoxy)phenyl]-3-(4-cyclopentyloxyphenyl)-1,3-dihydroimidazol-2-one

Procedure

1-(4-Cyclopentyloxyphenyl)-3-(4-hydroxyphenyl)-1,3-dihydroimidazol-2-one was reacted with 1,2-dibromoethane as described in example 5. The product with the molecular weight of 443.34 (C22H23BrN2O3); MS (ESI): 443 ([M+H]+) was obtained in this way.

Workup

  1. customMS (ESI): 443 ([M+H]+) was obtained in this way

Sources & evidence

ORD record
ord-5f0fdfaf5b074e999cac82f775b6a906
Source dataset
uspto-grants-2006_11
Patent number
US07141561B2

Reaction notes

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