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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 723370Generated: October 25, 2026

1H-1,2,4-Triazole → 1-(4-Cyclopentyloxyphenyl)-3-[4-(2-[1,2,4]triazol-4-ylethoxy)phenyl]-1,3-dihydroimidazol-2-one

https://huagongshe.com/reaction/723370

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-1,2,4-TriazoleHCID 9257—
Reactant1-[4-(2-Bromoethoxy)phenyl]-3-(4-cyclopentyloxyphenyl)-1,3-dihydroimidazol-2-oneHCID 21873330—
Product1-(4-Cyclopentyloxyphenyl)-3-[4-(2-[1,2,4]triazol-4-ylethoxy)phenyl]-1,3-dihydroimidazol-2-oneHCID 21873321—

Reaction Steps

1-[4-(2-Bromoethoxy)phenyl]-3-(4-cyclopentyloxyphenyl)-1,3-dihydroimidazol-2-one was reacted with 1,2,4-triazole as described in example 5. The product with the molecular weight of 431.50 (C24H25N5O3); MS (ESI): 432 ([M+H]+) was obtained in this way.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07141561B2
Source datasetuspto-grants-2006_11
ORD IDord-9cdb71c81e214bcd9b51e4e4364b17b7
Source noteuspto-grants-2006_11