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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 723377Generated: October 25, 2026

1-(4-Aminophenyl)-3-(4-phenoxyphenyl)-1,3-dihydroimidazol-2-one → 2-(Acetylmethylamino)-N-{4-[2-oxo-3-(4-phenoxyphenyl)-2,3-dihydroimidazol-1-yl]phenyl}acetamide

https://huagongshe.com/reaction/723377

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Aminophenyl)-3-(4-phenoxyphenyl)-1,3-dihydroimidazol-2-oneHCID 10246828—
Reactant(Acetylmethylamino)acetic acidHCID 21873483—
Product2-(Acetylmethylamino)-N-{4-[2-oxo-3-(4-phenoxyphenyl)-2,3-dihydroimidazol-1-yl]phenyl}acetamideHCID 21873335—

Reaction Steps

1-(4-Aminophenyl)-3-(4-phenoxyphenyl)-1,3-dihydroimidazol-2-one was reacted with (acetylmethylamino)acetic acid as described in example 217. The product with the molecular weight of 456.51 (C26H24N4O4); MS (ESI): 457 ([M+H] ) was obtained as hydrotrifluoroacetate in this way.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07141561B2
Source datasetuspto-grants-2006_11
ORD IDord-a230db8571f743bda696a9f6e38c50ca
Source noteuspto-grants-2006_11