反应详情

To (1R,3R,4R)-4-azido-3-hydroxy-cyclohexanecarboxylic acid amide (351c) (765 mg, 4.15 mmol) in MeOH/AcOH (9:1, 30 mL) was added Pd/C (10%, 300 mg), and the mixture hydrogenated under atmospheric pressure for 22 h. On completion of reaction the mixture was filtered through Celite®, the filter pad washed with MeOH, and the combined organic solutions concentrated in vacuo to give a white solid in quantitative yield.

1. customOn completion of reaction the mixture
2. filtrationwas filtered through Celite®
3. washthe filter pad washed with MeOH
4. concentrationthe combined organic solutions concentrated in vacuo
5. customto give a white solid in quantitative yield