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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 723765Generated: November 4, 2026

Hydrochloric Acid → HCID 69363411, compound

https://huagongshe.com/reaction/723765

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 69364434HCID 69364434—
SolventEthanolHCID 702—
SolventDichloromethaneHCID 6344—
ProductHCID 69363411HCID 69363411—

Reaction Steps

(5R)-3-(4-((3S)-3-(t-Butoxycarbonyl)aminopyrrolidin-1-yl)-3-fluorophenyl)-5-(1,2,3-triazol-1-ylmethyl)oxazolidin-2-one (1.55 g, 3.47 mM), was dissolved in dichloromethane (8 ml), and treated with a solution of hydrogen chloride in ethanol (3.8M, 40 ml). After stirring 2 hours at ambient temperature, the mixture was evaporated to dryness to give product as a hydrochloride of sufficient quality to require no purification (1.64 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07141583B2
Source datasetuspto-grants-2006_11
ORD IDord-ad89c63ff1974999957ed7cfcd0625b7
Source noteuspto-grants-2006_11