HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 69365920, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 69365257 | HCID 69365257 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 69365920 | HCID 69365920 | 63.8% |
Reaction Steps
(5R)-3-(4-(1-(2-Acetoxyacetyl)-1,2,5,6-tetrahydropyridin-4-yl)-3-fluorophenyl)-5-(tetrazol-2-ylmethyl)oxazolidin-2-one (365 mg, 0.82 mM) was treated with a saturated solution of ammonia in methanol (40 ml), warmed slightly to dissolve completely, then stirred at room temperature for 20 hours. The solvent was evaporated to give an orange oil which was triturated with diethyl ether to give the title compound as a pale yellow solid (211 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07141583B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-a7b42de2374e44da8b984fac397be570 |
| Source note | uspto-grants-2006_11 |