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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 723798Generated: October 30, 2026

Ammonia → HCID 69365920, compound

https://huagongshe.com/reaction/723798

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantHCID 69365257HCID 69365257—
SolventMethanolHCID 887—
ProductHCID 69365920HCID 6936592063.8%

Reaction Steps

(5R)-3-(4-(1-(2-Acetoxyacetyl)-1,2,5,6-tetrahydropyridin-4-yl)-3-fluorophenyl)-5-(tetrazol-2-ylmethyl)oxazolidin-2-one (365 mg, 0.82 mM) was treated with a saturated solution of ammonia in methanol (40 ml), warmed slightly to dissolve completely, then stirred at room temperature for 20 hours. The solvent was evaporated to give an orange oil which was triturated with diethyl ether to give the title compound as a pale yellow solid (211 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07141583B2
Source datasetuspto-grants-2006_11
ORD IDord-a7b42de2374e44da8b984fac397be570
Source noteuspto-grants-2006_11