2,6-Benzothiazolediamine → HCID 178511935, compound

HRID 723946Notes

Reaction equation

HRID 723946 reaction equation
[S:1]1[C:5]2[CH:6]=[C:7]([NH2:10])[CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[NH2:11].Br.C1(S[C:20]([C:22]2[S:23][CH:24]=[CH:25][CH:26]=2)=[NH:21])C=CC=CC=1>CCOCC>[NH2:11][C:2]1[S:1][C:5]2[CH:6]=[C:7]([NH:10][C:20]([C:22]3[S:23][CH:24]=[CH:25][CH:26]=3)=[NH:21])[CH:8]=[CH:9][C:4]=2[N:3]=1

Participants

4

Reactant 2

HCID 215042,6-BenzothiazolediamineHCID 66912440Thiophene-2-carboximidothioic acid phenyl ester hydrobromide

Product 1

HCID 178511935HCID 178511935, compoundYield 94%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A mixture of benzothiazole-2,6-diamine (Example 1, 50 mg, 0.3 mmol) and thiophene-2-carboximidothioic acid phenyl ester hydrobromide (91 mg, 0.3 mmol) was stirred at room temperature for 17 hours. After this time a precipitate formed. The mixture was diluted with 4 mL of Et2O and filtered to give the title compound. Yield: 94%, 1H-NMR (DMSO-d6): δ 11.30 (br s, 1H); 9.71 (s, 1H); 8.80 (s, 1H); 8.18 (m, 2H); 7.74 (m, 3H); 7.29 (m, 3H).

Workup

  1. customAfter this time a precipitate formed
  2. filtrationfiltered

Sources & evidence

ORD record
ord-860257c8bc58408b959d699bd7e2e8ff
Source dataset
uspto-grants-2006_11
Patent number
US07141595B2

Reaction notes

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