HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluorophenol → 1-Benzhydryl-3-(3-fluorophenoxy)azetidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluorophenol | HCID 9743 | — |
| Reactant | 1-(Diphenylmethyl)azetidin-3-yl methanesulfonate | HCID 2758716 | — |
| Product | 1-Benzhydryl-3-(3-fluorophenoxy)azetidine | HCID 19799621 | 80.9% |
Reaction Steps
The title compound (D22) (1.93 g) was prepared according to the experimental procedure described in Description 21 starting from 1-benzhydrylazetidin-3-yl methanesulfonate (D19) (2.5 g, 7.87 mmol) and 3-fluorophenol (0.642 ml, 7.16 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08828987B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-83dabc3e49b94d36991f1f54a4471d05 |
| Source note | uspto-grants-2014_09 |