Valeryl chloride → HCID 67099220, compound

HRID 724032Notes

Reaction equation

[NH2:1][C:2]1[C:3]([NH:11][C:12]2[CH:17]=[CH:16][C:15]([CH2:18][CH2:19][OH:20])=[CH:14][CH:13]=2)=[N:4][C:5]([CH3:10])=[C:6]([Br:9])[C:7]=1[CH3:8].[C:21](Cl)(=[O:26])[CH2:22][CH2:23][CH2:24][CH3:25]>>[C:21]([O:20][CH2:19][CH2:18][C:15]1[CH:16]=[CH:17][C:12]([N:11]2[C:3]3=[N:4][C:5]([CH3:10])=[C:6]([Br:9])[C:7]([CH3:8])=[C:2]3[N:1]=[C:10]2[CH2:5][CH2:6][CH2:7][CH3:2])=[CH:13][CH:14]=1)(=[O:26])[CH2:22][CH2:23][CH2:24][CH3:25]

Participants

Reactant 2

HCID 61186Valeryl chloride

HCID 21875575HCID 21875575, compound

Product 1

HCID 67099220HCID 67099220, compound

Procedure

The title compound was prepared according to the procedure described in step 5 of Example 1 from 2-{4-[(3-amino-5-bromo-4,6-dimethyl-2-pyridinyl)amino]phenyl}ethanol (step 4 of Example 9) and pentanoyl chloride.

Sources & evidence

ORD record: ord-43576c40531b4a8e9a14a267d7344cd2
Source dataset: uspto-grants-2006_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07141580B2

Reaction notes

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