4-Aminophenethyl alcohol → 2-[4-(3,5-Dimethyl-2-nitroanilino)phenyl]ethanol

HRID 724089Notes

Reaction equation

HRID 724089 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[C:5]([N+:9]([O-:11])=[O:10])=[C:4](F)[CH:3]=1.[NH2:13][C:14]1[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][OH:22])=[CH:16][CH:15]=1>>[CH3:8][C:6]1[C:5]([N+:9]([O-:11])=[O:10])=[C:4]([CH:3]=[C:2]([CH3:1])[CH:7]=1)[NH:13][C:14]1[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][OH:22])=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 669044-Aminophenethyl alcoholHCID 218759151-Fluoro-3,5-dimethyl-2-nitrobenzene

Product 1

HCID 218756512-[4-(3,5-Dimethyl-2-nitroanilino)phenyl]ethanol

Procedure

The title compound was prepared according to the procedure described in step 3 of Example 1 from 4,6-dimethyl-2-fluoronitrobenzene and 4-aminophenylethyl alcohol.

Sources & evidence

ORD record
ord-de518ec8f7f2430f8540a548adbbb1c2
Source dataset
uspto-grants-2006_11
Patent number
US07141580B2

Reaction notes

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