HRID724129

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID72871

3-Benzoylpropionic acid

C10H10O3

结构：Cc1ccc(S(=O)(=O)NC(=O)NCCc2ccc(Nc3nc(C)cc(C)c3N)cc2)cc1

HCID21875620

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc(S(=O)(=O)NC(=O)NCCc2ccc(-n3c(CCC(=O)c4ccccc4)nc4c(C)cc(C)nc43)cc2)cc1

HCID21875545

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the procedure described in Example 241 from N-{[(2-{4-[(3-amino-4,6-dimethyl-2-pyridinyl)amino]phenyl}ethyl)amino]carbonyl}4-methylbenzenesulfonamide (step 4 of Example 162) and 3-benzoylpropionic acid.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-939ba47e1a4e4969876a38319cc9d95c
来源数据集: uspto-grants-2006_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07141580B2
来源说明: uspto-grants-2006_11

反应 SMILES

[NH2:1][C:2]1[C:3]([NH:10][C:11]2[CH:16]=[CH:15][C:14]([CH2:17][CH2:18][NH:19][C:20]([NH:22][S:23]([C:26]3[CH:31]=[CH:30][C:29]([CH3:32])=[CH:28][CH:27]=3)(=[O:25])=[O:24])=[O:21])=[CH:13][CH:12]=2)=[N:4][C:5]([CH3:9])=[CH:6][C:7]=1[CH3:8].[C:33]([CH2:41][CH2:42][C:43](O)=O)(=[O:40])[C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1>>[CH3:9][C:5]1[N:4]=[C:3]2[N:10]([C:11]3[CH:16]=[CH:15][C:14]([CH2:17][CH2:18][NH:19][C:20]([NH:22][S:23]([C:26]4[CH:27]=[CH:28][C:29]([CH3:32])=[CH:30][CH:31]=4)(=[O:25])=[O:24])=[O:21])=[CH:13][CH:12]=3)[C:43]([CH2:42][CH2:41][C:33](=[O:40])[C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=3)=[N:1][C:2]2=[C:7]([CH3:8])[CH:6]=1