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1-(6-Chloro-5-nitropyridin-3-yl)ethanone → 1-[6-({4-[2-Hydroxypropyl]phenyl}amino)-5-nitro-3-pyridinyl]ethanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(6-Chloro-5-nitropyridin-3-yl)ethanone | HCID 14762705 | — |
| 反応物 | 1-(4-Aminophenyl)-2-propanol | HCID 21875672 | — |
| 生成物 | 1-[6-({4-[2-Hydroxypropyl]phenyl}amino)-5-nitro-3-pyridinyl]ethanone | HCID 21875957 | — |
反応手順
The title compound was prepared according to the procedure described in step 1 of Example 162 from 1-(6-chloro-5-nitro-3-pyridinyl)ethanone (Paul, B. et al. J. Med. Chem., 1990, 33, 2231–2239.) and 1-(4-aminophenyl)-2-propanol (step 1 of Example 6).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07141580B2 |
| 出典データセット | uspto-grants-2006_11 |
| ORD ID | ord-17984cbc670949a6ac9510cc0c895734 |
| 出典メモ | uspto-grants-2006_11 |