HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isoquinoline-5-sulfonamide → 2-{4-[6-Chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-YL]phenyl}ethyl-5-isoquinolinylsulfonylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isoquinoline-5-sulfonamide | HCID 9837177 | — |
| Reactant | 2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl phenyl carbonate | HCID 21876409 | — |
| Product | 2-{4-[6-Chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-YL]phenyl}ethyl-5-isoquinolinylsulfonylcarbamate | HCID 21876099 | — |
Reaction Steps
The title compound was prepared according to the procedure described in step 2 of Example 243 from 2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl phenyl carbonate and 5-isoquinolinylsulfonamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07141580B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-4faa1e49404d4412a4f37dc2afcf71b1 |
| Source note | uspto-grants-2006_11 |