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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 724164Generated: October 31, 2026

1,2-dimethyl-1H-imidazole-4-sulfonamide → 2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl-(1,2-dimethyl-1H-imidazol-4-yl)sulfonylcarbamate

https://huagongshe.com/reaction/724164

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-dimethyl-1H-imidazole-4-sulfonamideHCID 2758563—
Reactant2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl phenyl carbonateHCID 21876409—
Product2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl-(1,2-dimethyl-1H-imidazol-4-yl)sulfonylcarbamateHCID 21876048—

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 243 from 2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl phenyl carbonate and 1,2-dimethyl-1H-imidazol-4-ylsulfonamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07141580B2
Source datasetuspto-grants-2006_11
ORD IDord-9ff968533bd54b17a727313ae84e9a02
Source noteuspto-grants-2006_11