HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluorophenol → (R)-tert-butyl 2-((3-fluorophenoxy)methyl)pyrrolidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluorophenol | HCID 9743 | — |
| Reactant | N-(tert-Butoxycarbonyl)-D-prolinol | HCID 688279 | — |
| Product | (R)-tert-butyl 2-((3-fluorophenoxy)methyl)pyrrolidine-1-carboxylate | HCID 22857708 | 86% |
Reaction Steps
The title compound (D42) (D021/047/1) (252.3 mg) was prepared according to the experimental procedure described in Description 40 starting from (R)-tert-butyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate (D41) (200 mg, 0.993 mmol) and 3-Fluorophenol (0.089 ml, 0.993 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08828987B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-33455f0201f7472da779c13f49e16a74 |
| Source note | uspto-grants-2014_09 |