Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Fluorophenol → (S)-tert-butyl 3-(3-fluorophenoxy)pyrrolidine-1-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Fluorophenol | HCID 9743 | — |
| 반응물 | tert-Butyl (3R)-3-hydroxypyrrolidine-1-carboxylate | HCID 6544479 | — |
| 생성물 | (S)-tert-butyl 3-(3-fluorophenoxy)pyrrolidine-1-carboxylate | HCID 67958745 | 98.1% |
반응 단계
The title compound (D46) (294.6 mg) was prepared according to the experimental procedure described in Description 40 starting from (R)-tert-butyl 3-hydroxypyrrolidine-1-carboxylate (200 mg, 1.068 mmol, available at Aldrich#532169) and 3-Fluorophenol (0.096 ml, 1.068 mmol).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08828987B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-e71136b902904846aae480ce70cb3576 |
| 출처 메모 | uspto-grants-2014_09 |