HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 724213Generated: October 31, 2026
Dimethylformamide → 6-Bromo-2-naphthoyl chloride
https://huagongshe.com/reaction/724213
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 6-Bromo-2-naphthalenecarboxylic acid | HCID 4549852 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 6-Bromo-2-naphthoyl chloride | HCID 21879606 | — |
Reaction Steps
A suspension of 6-bromo-2-naphthoic acid (100 g), thionyl chloride (37.7 ml) and DMF (0.5 ml) in THF (1000 ml) was stirred at 60° C. with heating for 90 min. After cooling to room temperature, the solvent was evaporated under reduced pressure. The resulting solid was dissolved in toluene and the solvent was evaporated to give 6-bromo-2-naphthoyl chloride as a pale yellow powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07141598B2 |
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| Source dataset | uspto-grants-2006_11 |
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| ORD ID | ord-8467ed91b5ef477590f53d5db49c210d |
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| Source note | uspto-grants-2006_11 |
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