HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Trimethylsilyldiazomethane → Methyl 2-chloro-5-fluoronicotinate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Trimethylsilyldiazomethane | HCID 167693 | — |
| Edukt | 2-Chloro-5-fluoronicotinic acid | HCID 11435243 | — |
| Produkt | Methyl 2-chloro-5-fluoronicotinate | HCID 24229209 | 83,4% |
Reaktionsschritte
The title compound (D69) (0022/105/1) (1.8 g) was prepared according to the experimental procedure described in Description 66 starting from 2-Chloro-5-fluoronicotinic acid (2 g, 11.39 mmol) and trimethylsilyldiazomethane (2M solution in diethyl ether) (17 ml, 34.18 mmol)
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08828987B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-3f6d446cdb1b4a22937cf879919aa8b4 |
| Quellennotiz | uspto-grants-2014_09 |